Gastrointestinal stromal tumours (GISTs) are rare cancers that develop in the digestive system. They are a type of soft tissue sarcoma. Most GISTs start in the stomach or small bowel. But they can develop anywhere along the length of the digestive system, including in the:

  • Gullet (oesophagus)
  • Back passage (rectum)

Very rarely, they can develop outside the digestive system. Every year, about 900 people in the UK are diagnosed with a GIST. GIST’s are most common in people who are aged 50 and over, and it is rare in people who are less than aged 40 years. 
       
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